GABBR1 Antibody (N-Term) [APG03311G]

• Background:

  Tissue Location: Highly expressed in brain (PubMed:9844003, PubMed:9753614, PubMed:9872744) . Weakly expressed in heart, small intestine and uterus. Isoform 1A: Mainly expressed in granular cell and molecular layer (PubMed:9844003) . Isoform 1B: Mainly expressed in Purkinje cells (PubMed:9844003) . Isoform 1E: Predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland (PubMed:10906333)

• Synonyms:

  Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, GABBR1, GPRC3A

• Gene Name:

  GABBR1

• Gene ID:

  2550

• UniProt:

  Q9UBS5

• Chromosomal Location:

  Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9Z0U4}; Multi-pass membrane protein. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9Z0U4}. Note=Colocalizes with ATF4 in hippocampal neuron dendritic membranes (By similarity) . Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane (PubMed:15617512) . {ECO:0000250|UniProtKB:Q9Z0U4, ECO:0000269|PubMed:15617512}

• Applications:

  WB

• Dilution:

  WB--1:2000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  98723169872744156175121816568822660477243050541816568810906333107730161007564498727442430505410075644984400398440039872316100756449872744226604779844003987231624305054

• Molecular Weight:

  108320

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GABBR1 Antibody (N-Term) [APG03311G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=2550

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UBS5