EPS15R Antibody (N-term) [APR15852G]

• Synonyms:

  Epidermal growth factor receptor substrate 15-like 1, Eps15-related protein, Eps15R, EPS15L1, EPS15R

• Gene Name:

  EPS15L1

• Gene ID:

  58513

• UniProt:

  Q9UBC2

• Chromosomal Location:

  Cell membrane; Peripheral membrane protein. Nucleus. Membrane, coated pit. Note=Localized to plasma membrane coated pits

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

• Function:

  Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR) ; internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.

• Molecular Weight:

  94255

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EPS15R Antibody (N-term) [APR15852G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=58513

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UBC2