Vitexin

• Description:

  Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Autophagy

• Type:

  Natural Products

• Related Pathways:

  Autophagy

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/vitexin.html

• Concentration:

  10mM

• Purity:

  99.90

• Solubility:

  DMF : 4 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  OC1=CC=C (C2=CC (C (C (O) =CC (O) =C3[C@H]4[C@H] (O) [C@@H] (O) [C@H] (O) [C@@H] (CO) O4) =C3O2) =O) C=C1

• Molecular Formula:

  C21H20O10

• Molecular Weight:

  432.38

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]He M, et al. A review on the pharmacological effects of vitexin and isovitexin. Fitoterapia. 2016 Dec;115:74-85.|[2] Lima LKF, et al. A Brief Review on the Neuroprotective Mechanisms of Vitexin. Biomed Res Int. 2018 Dec 5;2018:4785089.|[3]Jiang J, Dai J, Cui H. Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway. Biomed Pharmacother. 2018;99:583-590.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  3681-93-4