Vitexin

• Description :

  Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Autophagy

• Type :

  Natural Products

• Related Pathways :

  Autophagy

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/vitexin.html

• Concentration :

  10mM

• Purity :

  99.90

• Solubility :

  DMF : 4 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  OC1=CC=C(C2=CC(C(C(O)=CC(O)=C3[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)=C3O2)=O)C=C1

• Molecular Formula :

  C21H20O10

• Molecular Weight :

  432.38

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]He M, et al. A review on the pharmacological effects of vitexin and isovitexin. Fitoterapia. 2016 Dec;115:74-85.|[2] Lima LKF, et al. A Brief Review on the Neuroprotective Mechanisms of Vitexin. Biomed Res Int. 2018 Dec 5;2018:4785089.|[3]Jiang J, Dai J, Cui H. Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway. Biomed Pharmacother. 2018;99:583-590.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [3681-93-4]