ATG9A Antibody (C-term) [APR07027G]

• Synonyms:

  Autophagy-related protein 9A, APG9-like 1, mATG9, ATG9A, APG9L1

• Gene Name:

  ATG9A {ECO:0000303|PubMed:20124090, ECO:0000312|HGNC:HGNC:22408}

• Gene ID:

  79065

• UniProt:

  Q7Z3C6

• Chromosomal Location:

  Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi- pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Mainly localizes to the trans-Golgi network (TGN) and the endosomal system; cycles between them though vesicle trafficking (PubMed:27316455, PubMed:27663665) . Export from the TGN to promote formation of autophagosomes is mediated by the AP-4 complex (PubMed:29180427, PubMed:30262884) . Under amino acid starvation or rapamycin treatment, redistributes to preautophagosomal structure/phagophore assembly site (PAS) (PubMed:16940348) . The starvation-induced redistribution depends on ULK1, ATG13, as well as SH3GLB1 (PubMed:16940348) . Upon autophagy induction, a small portion transiently localizes to the autophagic membranes (PubMed:22456507) .

• Applications:

  IF, WB, IHC-P

• Dilution:

  WB--1:1000 IF--1:100 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  22456507275109222943769532513819334686223385002332610138331066591694034822456507331066593310665930917996

• Molecular Weight:

  94447

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATG9A Antibody (C-term) [APR07027G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=79065

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q7Z3C6