RFNG Antibody (C-term) [APR13087G]

• Synonyms:

  Beta-1,3-N-acetylglucosaminyltransferase radical fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, RFNG

• Gene Name:

  RFNG

• Gene ID:

  5986

• UniProt:

  Q9Y644

• Chromosomal Location:

  Golgi apparatus membrane; Single- pass type II membrane protein

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in enhancement of NOTCH1 activation by DLL1 and JAG1. May be involved in limb formation and in neurogenesis.

• Molecular Weight:

  36424

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RFNG Antibody (C-term) [APR13087G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5986

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y644