HTATIP2 Antibody (N-term) [AMM05388G]

• Background:

  Tissue Location: Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas.

• Synonyms:

  HGNC:16637

• Gene Name:

  HGNC:16637

• Gene ID:

  10553

• UniProt:

  Q9BUP3

• Chromosomal Location:

  Cytoplasm. Nucleus envelope

• Applications:

  WB, IHC-P

• Dilution:

  WB--1:1000 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.

• Molecular Weight:

  27049

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HTATIP2 Antibody (N-term) [AMM05388G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=10553

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BUP3