DRAGON (RGMB) Antibody (Center) [APR11799G]

• Synonyms:

  RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB

• Gene Name:

  RGMB {ECO:0000303|PubMed:19324014, ECO:0000312|HGNC:HGNC:26896}

• Gene ID:

  285704

• UniProt:

  Q6NW40

• Chromosomal Location:

  Cell membrane {ECO:0000250|UniProtKB:Q7TQ33}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q7TQ33}. Membrane raft {ECO:0000250|UniProtKB:Q7TQ33}

• Applications:

  WB, IHC-P

• Dilution:

  WB--1:1000 IHC-P--1:100~500

• Form:

  Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

• Function:

  Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity) . Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity) . Promotes neuronal adhesion (By similarity) . May inhibit neurite outgrowth.

• Molecular Weight:

  47547

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DRAGON (RGMB) Antibody (Center) [APR11799G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=285704

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6NW40