Nucleostemin (GNL3) Antibody (C-term) [AMM06861G]

• Background:

  Tissue Location: Increased levels in lung tissue in cancer patients.

• Synonyms:

  Guanine nucleotide-binding protein-like 3, E2-induced gene 3 protein, Novel nucleolar protein 47, NNP47, Nucleolar GTP-binding protein 3, Nucleostemin, GNL3, E2IG3, NS

• Gene Name:

  GNL3

• Gene ID:

  26354

• UniProt:

  Q9BVP2

• Chromosomal Location:

  Nucleus {ECO:0000250|UniProtKB:Q811S9}. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}

• Applications:

  WB, IHC-P

• Dilution:

  WB--1:1000 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity) .

• Molecular Weight:

  61993

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Nucleostemin (GNL3) Antibody (C-term) [AMM06861G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=26354

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BVP2