Twinfilin-2 (PTK9L) Antibody (C-term) [APR14076G]

• Background:

  Tissue Location: Ubiquitously expressed (at protein level) .

• Synonyms:

  Twinfilin-2, A6-related protein, hA6RP, Protein tyrosine kinase 9-like, Twinfilin-1-like protein, TWF2, PTK9L

• Gene Name:

  TWF2

• Gene ID:

  11344

• UniProt:

  Q6IBS0

• Chromosomal Location:

  Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, stereocilium. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity) .

• Molecular Weight:

  39548

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Twinfilin-2 (PTK9L) Antibody (C-term) [APR14076G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=11344

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6IBS0