APG8a/b (MAP1LC3A/B) Antibody [APG01921G]

• Background:

  Tissue Location: Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver

• Synonyms:

  Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B, Microtubule-associated protein 1 light chain 3 beta, MAP1LC3B, MAP1ALC3

• Gene Name:

  HGNC:13352

• Gene ID:

  81631

• UniProt:

  Q9GZQ8

• Chromosomal Location:

  Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes. LC3-II localizes with the mitochondrial inner membrane during Parkin-mediated mitophagy (PubMed:28017329) . Localizes also to discrete punctae along the ciliary axoneme

• Applications:

  IF, WB, IHC-P

• Dilution:

  IF--1:100 WB--1:1000 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  28017329229227583100653831006537

• Molecular Weight:

  14688

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APG8a/b (MAP1LC3A/B) Antibody [APG01921G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=81631

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9GZQ8