Lemnalol

CAT: 0804-HY-121239Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-121239Size:1 Each

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Description

Lemnalol is a potent agent for neuropathic pain. Lemnalol possesses potent anti-inflammatory, analgesic and anti-tumor activities. Lemnalol has the capacity to attenuate hyperalgesia and allodynia by modulation of neuroinflammatory processes in neuropathy. Lemnalol modulates LPS-induced alterations of left atrial (LA) calcium homeostasis and blocks the NF-κB pathways, which may contribute to the attenuation of lipopolysaccharide (LPS) -induced arrhythmogenesis and neuropathic pain. Lemnalolis a ylangene-type sesquiterpenoid compound, isolated from Lemnalia cervicorni[1][2].

CAS Number

82570-34-1

UNSPSC

12352211

Target

NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lemnalol.html

Smiles

CC([C@H]1[C@@]2([H])[C@@]3([H])[C@]([C@]2([H])C[C@H](C3=C)O)(CC1)C)C

Molecular Formula

C15H24O

Molecular Weight

220.35

References & Citations

[1]Tai BY, et al. Lemnalol Modulates the Electrophysiological Characteristics and Calcium Homeostasis of Atrial Myocytes. Mar Drugs. 2019 Oct 30;17 (11) :619.|[2]Lin YC, et al. Intrathecal lemnalol, a natural marine compound obtained from Formosan soft coral, attenuates nociceptive responses and the activity of spinal glial cells in neuropathic rats. Behav Pharmacol. 2011 Dec;22 (8) :739-50.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

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