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Tadnersen

CAT: 0804-HY-132581-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132581-01Size:1 mg
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Description
Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion[1].
CAS Number
2170507-65-8
Product Name Alternative
BIIB078; IONIS-C9Rx
UNSPSC
12352208
Target
Others; Ras
Type
Oligonucleotides
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tadnersen.html
Purity
99.30
Solubility
H2O : ≥ 100 mg/mL
Smiles
[Tadnersen]
References & Citations
[1]Smeyers J, et al. C9ORF72: What It Is, What It Does, and Why It Matters. Front Cell Neurosci. 2021;15:661447. Published 2021 May 5.|[2]Aoki Y, et al. Emerging Oligonucleotide Therapeutics for Rare Neuromuscular Diseases [published online ahead of print, 2021 Jun 3]. J Neuromuscul Dis. 2021;10.3233/JND-200560.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 3

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