Luteolin 5-O-glucoside

Luteolin 5-O-glucoside

• CAS Number: 20344-46-1
• UNSPSC Description: Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages[1].
• Target Antigen: NO Synthase; Reactive Oxygen Species
• Type: Natural Products
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/luteolin-5-o-glucoside.html
• Purity: 98.0
• Solubility: 10 mM in DMSO
• Smiles: O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C13
• Molecular Weight: 448.38
• References & Citations: [1]Anti-inflammatory activity of Korean thistle Cirsium maackii and its major flavonoid, luteolin 5-O-glucoside.Food Chem Toxicol. 2012 Jun;50(6):2171-9.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported