Amitifadine (hydrochloride)
CAT:
804-HY-18332A-04
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Amitifadine (hydrochloride)
- CAS Number: 410074-74-7
- UNSPSC Description: Amitifadine hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI), with IC50s of 12, 23, 96 nM for serotonin, norepinephrine and dopamine in HEK 293 cells , respectively.
- Target Antigen: Dopamine Transporter; Serotonin Transporter
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/Amitifadine-hydrochloride.html
- Purity: 99.64
- Solubility: DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)
- Smiles: ClC(C=C1[C@]2(CNC3)[C@@H]3C2)=C(C=C1)Cl.[H]Cl
- Molecular Weight: 264.58
- References & Citations: [1]Skolnick P1, et al. Antidepressant-like actions of DOV 21,947: a "triple" reuptake inhibitor. Eur J Pharmacol. 2003 Feb 14;461(2-3):99-104.|[2]Levin ED, et al. Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats. Eur J Pharmacol. 2015 Jun 20;764:30-37.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Phase 3