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Pezadeftide

CAT: 0804-HY-P3384Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P3384Size:1 Each
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Description
Pezadeftide is a potent antifungal peptide. Pezadeftide can enter fungal cells and cause a rapid mitochondrial response that results in hyperpolarization of the mitochondrial membrane[1].
CAS Number
1907724-92-8
UNSPSC
12352209
Target
Antibiotic
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Others
Assay Protocol
https://www.medchemexpress.com/pezadeftide.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CSSC[C@@H](C(O)=O)NC1=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@H]6C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC7=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](C)C(N[C@@H](CSSC[C@@H](C(N[C@H]8C(C)C)=O)NC6=O)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@H]1CC9=CNC=N9)=O)=O)=O)NC8=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CC%10=CNC=N%10)C(N[C@@H](CO)C(NCC(N[C@H]7CC%11=CC=C(C=C%11)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N
Molecular Formula
C234H372N70O66S8
Molecular Weight
5478.41
References & Citations
[1]Nicole L, et al. 32994 Pezadeftide is a potent antifungal peptide with rapid fungicidial activity via a unique mechanism of action. J AM ACAD DERMATOL. 2022, 87, 3.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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