Anti-Hu CD167a PE

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

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Anti-Hu CD167a PE

CAT:

270-1P-132-T100

Size:

100 Tests

Price:

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For price, please contact [email protected].

Anti-Hu CD167a PE

Background: CD167a, also known as e.g. discoidin domain receptor tyrosine kinase 1 (DDR1), tyrosine kinase receptor E (TRKE), cell adhesion kinase (CAK), or neuroepithelial tyrosine kinase 4 (NEP, NTRK4), is a transmembrane receptor tyrosine kinase expressed predominantly in epithelial cells. It has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. After binding to fibrilar collagens I, II, III, V, or basement membrane collagens IV and VIII, CD167a becomes activated and autophosphorylated and transduces collagen-induced signaling.
Specifications: The mouse monoclonal antibody 51D6 recognizes an extracellular epitope of CD167a, an approximately 97-101 kDa receptor tyrosine kinase expressed mainly on epithelial cells, but also on B cells and dendritic cells.
Certification: RUO
Host: Mouse
Species Reactivity: Human
Immunogen: CD167a-transfected NIH-3T3 cells
Target Antigen: CD167a
Isotype: IgM
Clone: 51D6
Applications: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 mL) is sufficient for 100 tests.
Validated Applications: FC
Format: PE
Buffer: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
References & Citations: *Masuda H, Anwar SS, Bühring HJ, Rao JR, Gargett CE: A novel marker of human endometrial mesenchymal stem-like cells. Cell Transplant. 201221(10):2201-14., URL: https://www.ncbi.nlm.nih.gov/pubmed/22469435,
Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

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