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M084

CAT: 0804-HY-133859-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-133859-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans[1].
CAS Number
51314-51-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/m084.html
Purity
99.56
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CCCCNC1=NC2=CC=CC=C2N1
Molecular Formula
C11H15N3
Molecular Weight
189.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Ai-Jun Ding, et al. Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way. Mol Cell Biochem. 2017 Feb;426 (1-2) :101-109.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
BA8006-25M084
T84900-01M084 hydrochloride

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