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Pyraclostrobin

CAT: 0804-HY-N6626-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6626-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pyraclostrobin is a highly effective and broad-spectrum strobilurin fungicide. Pyraclostrobin can induce oxidative DNA damage, mitochondrial dysfunction and autophagy through the activation of AMPK/mTOR signaling. Pyraclostrobin can be used to control crop diseases[1][2][3].
CAS Number
175013-18-0
UNSPSC
12352005
Hazard Statement
H315, H331, H410
Target
AMPK; Autophagy; Bacterial; Bcl-2 Family; Beclin1; Fungal; mTOR
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Autophagy; Epigenetics; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pyraclostrobin.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC(N(C1=C(C=CC=C1)COC2=NN(C3=CC=C(Cl)C=C3)C=C2)OC)=O
Molecular Formula
C19H18ClN3O4
Molecular Weight
387.82
Precautions
H315, H331, H410
References & Citations
[1]Wu M, et al. Characterization of hepatotoxic effects induced by pyraclostrobin in human HepG2 cells and zebrafish larvae [J]. Chemosphere, 2023, 340: 139732.|[2]Zhang C, et al. Acute and subchronic toxicity of pyraclostrobin in zebrafish (Danio rerio) [J]. Chemosphere, 2017, 188: 510-516.|[3]Li H, et al. Mitochondrial dysfunction-based cardiotoxicity and neurotoxicity induced by pyraclostrobin in zebrafish larvae [J]. Environmental Pollution, 2019, 251: 203-211.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bax; Bcl-2

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