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D595

CAT: 0804-HY-117542Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117542Size:1 Each
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Description
D595 is a phenylethylamine calcium channel blocker with potent negative inotropic activity. D595 has shown significant efficacy in its corresponding pharmacological studies, especially in inhibiting the uptake of monoamine neurotransmitters. D595 has high affinity in binding to the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET) . Structural adjustments of D595, especially changes in the hydroxyl stereochemistry, significantly affect its interaction with the transporters, showing a specific preference for stereoisomers[1].
CAS Number
16740-29-7
UNSPSC
12352101
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d595.html
Smiles
N#CC(CCCN(CCC1=CC=C(C(OC)=C1)OC)C)(C(C)C)C2=CC=C(C(Cl)=C2)Cl
Molecular Formula
C25H32Cl2N2O2
Molecular Weight
463.44
References & Citations
[1]Novel Potent Dopamine-Norepinephrine and Triple Reuptake Uptake Inhibitors Based on Asymmetric Pyran Template and Their Molecular Interactions with Monoamine Transporters
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported