[Val4] Angiotensin III

[Val4] Angiotensin III

• CAS Number: 100900-28-5
• UNSPSC Description: [Val4] Angiotensin III is an angiotension III peptide. [Val4] Angiotensin III is a potent full agonist of Gαq and βarr2 response, with pEC50 values of 8.31 and 8.44, respectively[1].
• Target Antigen: Angiotensin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/val4-angiotensin-iii.html
• Purity: 98.51
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: CC(O)=O.OC(C=C1)=CC=C1C[C@H](NC([C@H](C(C)C)NC([C@@H](N)CCCNC(N)=N)=O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)=O
• Molecular Weight: 977.12
• References & Citations: [1]Namkung Y, et al. Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors. Sci Signal. 2018 Dec 4;11(559):eaat1631.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported