Aureobasidin A
CAT:
804-HY-P1975-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Aureobasidin A
- CAS Number: 127785-64-2
- UNSPSC Description: Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity[1][2][3].
- Target Antigen: Antibiotic; Fungal; Parasite
- Type: Peptides
- Related Pathways: Anti-infection
- Applications: COVID-19-immunoregulation
- Field of Research: Infection; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/aureobasidin-a.html
- Purity: 99.36
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C([C@@H](N(C([C@@H](NC([C@@H](N(C([C@@](OC1=O)([H])[C@H](C)CC)=O)C)C(C)C)=O)CC2=CC=CC=C2)=O)C)CC3=CC=CC=C3)N(CCC4)[C@]4([H])C(N[C@@](C(N([C@H](C(N[C@H](C(N([C@H]1C(C)(O)C)C)=O)CC(C)C)=O)C(C)C)C)=O)([H])[C@H](C)CC)=O
- Molecular Weight: 1101.42
- References & Citations: [1]Zheng L, et al. Chromosome 1 trisomy confers resistance to aureobasidin A in Candida albicans. Front Microbiol. 2023 Mar 17;14:1128160.|[2]Alqaisi AQI, et al. The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis. Parasitology. 2018 Feb;145(2):148-155.|[3]Takesako K, et al. Biological properties of aureobasidin A, a cyclic depsipeptide antifungal antibiotic. J Antibiot (Tokyo). 1993 Sep;46(9):1414-20.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported