2-Deoxy-D-glucose-13C-1

2-Deoxy-D-glucose-13C-1

• CAS Number: 119897-50-6
• UNSPSC Description: 2-Deoxy-D-glucose-13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
• Target Antigen: Apoptosis; Hexokinase; HSV; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Anti-infection;Apoptosis;Metabolic Enzyme/Protease;Others
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-deoxy-d-glucose-13c-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=CC[C@@H](O)[C@H](O)[C@H](O)[13CH2]O
• Molecular Weight: 165.15
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.;Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in r
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported