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Fluxapyroxad

CAT: 0804-HY-135549-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-135549-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. Fluxapyroxad inhibits succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species[1].
CAS Number
907204-31-3
UNSPSC
12352005
Hazard Statement
H351, H362, H410
Target
Antibiotic; Cytochrome P450; Fungal; Succinate Dehydrogenase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fluxapyroxad.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CN(C)N=C1C(F)F)NC2=CC=CC=C2C3=CC(F)=C(F)C(F)=C3
Molecular Formula
C18H12F5N3O
Molecular Weight
381.30
Precautions
H351, H362, H410
References & Citations
[1]Chen X, et al. Effective Monitoring of Fluxapyroxad and Its Three Biologically Active Metabolites in Vegetables, Fruits, and Cereals by Optimized QuEChERS Treatment Based on UPLC-MS/MS. J Agric Food Chem. 2016 Nov 23;64 (46) :8935-8943. |[2]Cao Y, et al., Fluxapyroxad induces chronic colonic inflammation via inhibiting intestinal aryl hydrocarbon receptors in mice. Sci Total Environ. 2025 Apr 10;973:179134.|[3]Chen X, et al., Fluxapyroxad disrupt erythropoiesis in zebrafish (Danio rerio) embryos. Ecotoxicol Environ Saf. 2022 Dec 1;247:114259.|[4]Bénit P, et al., Evolutionarily conserved susceptibility of the mitochondrial respiratory chain to SDHI pesticides and its consequence on the impact of SDHIs on human cultured cells. PLoS One. 2019 Nov 7;14 (11) :e0224132.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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