SC66

• UNSPSC Description:

  SC66 is an Akt inhibitor, reduces cell viability in a dose- and time-dependent manner, inhibits colony formation and induces apoptosis in hepatocellular carcinoma (HCC) cells.

• Target Antigen:

  Akt; Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/SC66.html

• Purity:

  99.47

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  O=C1/C(CCC/C1=C\C2=CC=NC=C2)=C/C3=CC=NC=C3

• Molecular Weight:

  276.33

• References & Citations:

  [1]Cusimano A, et al. Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells. Oncotarget. 2015 Jan 30;6(3):1707-22.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  871361-88-5