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CTK7A

CAT: 0804-HY-139804Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139804Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CTK7A is a curcumin derivative with anticancer activity by inhibiting the HAT activity of p300 and reducing the autoacetylation of p300, thereby affecting its interaction with HIF-1α. The inhibition of CTK7A leads to decreased HIF-1α accumulation and activity, which can be used for cancer treatment research[1].
CAS Number
1297262-16-8
UNSPSC
12352005
Target
Epigenetic Reader Domain; HIF/HIF Prolyl-Hydroxylase; Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ctk7a.html
Smiles
COC(C=C1/C=C/C2=CC(/C=C/C3=CC(OC)=C(C=C3)O)=NN2C4=CC=C(C=C4)C(O[Na])=O)=C(C=C1)O
Molecular Formula
C28H23N2NaO6
Molecular Weight
506.48
References & Citations
[1]Rath S, et al. CTK7A, a curcumin derivative, can be a potential candidate for targeting HIF-1α/p300 complex: Evidences from in vitro and computational studies[J]. Biophysical Chemistry, 2022, 287: 106828.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19197829-01CTK7A
217427Histone Acetyl Transferase Inhibitor VII, CTK7A (Sodium-4- (3,5-bis (4-hydroxy-3-methoxystyryl) -1H-pyrazol-1-yl) benzoate, HBC, Na, HAT Inhibitor VII, p300/CBP Inhibitor V, PCAF Inhibitor III)

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