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Evodenoson

CAT: 0804-HY-105017Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105017Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenoson’s primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenoson’s protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α) [1].
CAS Number
844873-47-8
Product Name Alternative
ATL 313; DE 112
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/evodenoson.html
Purity
99.9
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](O[C@@H]([C@H]1O)C(NC2CC2)=O)N3C4=NC(C#CCC5CCN(CC5)C(OC)=O)=NC(N)=C4N=C3
Molecular Formula
C23H29N7O6
Molecular Weight
499.52
References & Citations
[1]Cavalcante IC, et al. Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis. Infect Immun. 2006 May;74 (5) :2606-12.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Adenosine A2A receptor (A2AR)

Alternative Products

CatalogName
T31731-01Evodenoson

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