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ABBV-744

CAT: 0026-B3269-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B3269-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABBV-744 is a potent BDII (Bromodomain II)-selective (>100 X selectivity over BDI) BET bromodomain inhibitor. ABBV-744 inhibits proliferation of SKM-1 leukemia cells (IC50 = 6.7 nM). It induces cell cycle arrest at the G1 phase in LNCaP prostate cancer cells. ABBV-744 (18.8 mg/kg) reduces tumor volume in a SKM-1 mouse xenograft model.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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