Goitrin

• Description :

  Goitrin ((S) -Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity[1][2][3].

• Product Name Alternative :

  (S) -Goitrin; L-5-Vinyl-2-thiooxazolidone

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319

• Target :

  Influenza Virus

• Type :

  Natural Products

• Related Pathways :

  Anti-infection

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/goitrin.html

• Purity :

  99.66

• Solubility :

  10 mM in DMSO

• Smiles :

  S=C1O[C@@H](C=C)CN1

• Molecular Formula :

  C5H7NOS

• Molecular Weight :

  129.18

• Precautions :

  H302, H315, H319

• References & Citations :

  [1]Felker P, et, al. Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism. Nutr Rev. 2016 Apr;74 (4) :248-58.|[2]Wooding S, et, al. Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables. Chem Senses. 2010 Oct;35 (8) :685-92.|[3]Nie LX, et, al. Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action. J Ethnopharmacol. 2020 Apr 6;251:112550.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [500-12-9]