Goitrin

• UNSPSC Description:

  Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity[1][2][3].

• Target Antigen:

  Influenza Virus

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/goitrin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  S=C1O[C@@H](C=C)CN1

• Molecular Weight:

  129.18

• References & Citations:

  [1]Felker P, et, al. Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism. Nutr Rev. 2016 Apr;74(4):248-58.|[2]Wooding S, et, al. Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables. Chem Senses. 2010 Oct;35(8):685-92.|[3]Nie LX, et, al. Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action. J Ethnopharmacol. 2020 Apr 6;251:112550.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  500-12-9