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Goitrin

CAT: 0804-HY-N0224A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0224A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Goitrin ((S) -Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity[1][2][3].
CAS Number
[500-12-9]
Product Name Alternative
(S) -Goitrin; L-5-Vinyl-2-thiooxazolidone
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Influenza Virus
Type
Natural Products
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/goitrin.html
Purity
99.66
Solubility
10 mM in DMSO
Smiles
S=C1O[C@@H](C=C)CN1
Molecular Formula
C5H7NOS
Molecular Weight
129.18
Precautions
H302, H315, H319
References & Citations
[1]Felker P, et, al. Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism. Nutr Rev. 2016 Apr;74 (4) :248-58.|[2]Wooding S, et, al. Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables. Chem Senses. 2010 Oct;35 (8) :685-92.|[3]Nie LX, et, al. Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action. J Ethnopharmacol. 2020 Apr 6;251:112550.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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