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Toringin

CAT: 0804-HY-N4192-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N4192-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Toringin, a bioflavonoid, is isolated from the bark of Docyniopsis tschonoski. Toringin progressively decreases not only the cis-effect of the expanded CTG repeats but cytotoxicity as well. Exposure to isosakuranetin, Toringin rescues PC12 neuronal cells. Flavonoids are efficacious for ameliorating the RNA gain of function caused by expanded CTG repeats, and have various biological activities and beneficial actions against cancers, coronary heart disease, among other pathologies[1].
CAS Number
1329-10-8
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/toringin.html
Concentration
10mM
Purity
99.62
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C(OC(C2=CC=CC=C2)=C1)=CC(O)=C3)=C3O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO
Molecular Formula
C21H20O9
Molecular Weight
416.38
References & Citations
[1]Furuya H, et al. Some flavonoids and DHEA-S prevent the cis-effect of expanded CTG repeats in a stable PC12 cell transformant. Biochem Pharmacol. 2005 Feb 1;69 (3) :503-16.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
BUP21607Toringin

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