Regadenoson (hydrate)

CAT: 0804-HY-A0168ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-A0168ASize:1 Each
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Description
Regadenoson hydrate (NSC 169186) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson hydrate also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS[1][2].
CAS Number
[875148-45-1]
Product Name Alternative
CVT-3146 (hydrate)
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/regadenoson-hydrate.html
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=C(N=C2)C(N)=NC(N4C=C(C=N4)C(NC)=O)=N3)O1.O
Molecular Formula
C15H20N8O6
Molecular Weight
408.37
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Trochu JN, et al. Selective A2A adenosine receptor agonist as a coronary vasodilator in conscious dogs: potential for use in myocardial perfusion imaging. J Cardiovasc Pharmacol. 2003 Jan;41 (1) :132-9. |[2]Jackson S, et al. The effect of regadenoson-induced transient disruption of the blood-brain barrier on temozolomide delivery to normal rat brain. J Neurooncol. 2016 Feb;126 (3) :433-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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