(2R,3S)-Azelaprag

(2R,3S)-Azelaprag

• CAS Number: 2049979-31-7
• UNSPSC Description: (2R,3S)-Azelaprag ((2R,3S)-AMG 986) is an Apelin receptor agonist with an EC50 of 0.012 µM for Apelin receptors, and it is utilized in the treatment of various conditions such as heart failure, atherosclerosis, obesity, diabetes mellitus, amyotrophic lateral sclerosis, coronary artery disease, hypertension, stroke, and myocardial infarction.
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Metabolic Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/2r-3s-azelaprag.html
• Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=S(NC1=NN=C(C2=CN=CC(C)=C2)N1C(C(OC)=CC=C3)=C3OC)([C@H](C)[C@H](C4=NC=C(C)C=N4)C)=O
• Molecular Weight: 523.61
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported