Desogestrel

• Product Name Alternative:

  Org-2969

• UNSPSC Description:

  Desogestrel (Org-2969) is a third-generation progesterone analogue contained in many oral contraceptive preparations. Desogestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1][2][3][4].

• Target Antigen:

  Progesterone Receptor

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/Desogestrel.html

• Purity:

  99.65

• Solubility:

  DMSO : 16.67 mg/mL (ultrasonic)

• Smiles:

  [H][C@@]12C(CC[C@]([C@@](CC[C@@]3(O)C#C)([H])[C@]3(CC)C4)([H])[C@]2([H])C4=C)=CCCC1

• Molecular Weight:

  310.47

• References & Citations:

  [1]Gassen DT, et al. Evaluation of hormonal suppression with two contraceptive regimens using ethinyl estradiol and desogestrel. Arch Gynecol Obstet. 2013 Feb;287(2):289-94.|[2]Rosenberg MJ, et al. The effect of desogestrel, gestodene, and other factors on spotting and bleeding. Contraception. 1996 Feb;53(2):85-90.|[3]Barkfeldt J, et al. The effects of two progestogen-only pills containing either desogestrel (75 microg/day) or levonorgestrel (30 microg/day) on lipid metabolism. Contraception. 2001 Nov;64(5):295-9.|[4]Grandi G, et al. Pharmacokinetic evaluation of desogestrel as a female contraceptive. Expert Opin Drug Metab Toxicol. 2014 Jan;10(1):1-10.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Launched

• CAS Number:

  54024-22-5