SIRT4-IN-1

CAT:

804-HY-163316-06

Size:

100 mg

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UNSPSC Description: SIRT4-IN-1 (compound 69) is selective sirtuin 4 (Sirt4) inhibitor with an IC50 of 16 μM.SIRT4-IN-1 shows no relevant effects on other sirtuin isoforms[1].
Target Antigen: Sirtuin
Type: Reference compound
Related Pathways: Cell Cycle/DNA Damage;Epigenetics
Applications: Metabolism-protein/nucleotide metabolism
Field of Research: Cancer; Metabolic Disease
Assay Protocol: https://www.medchemexpress.com/sirt4-in-1.html
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: O=C1C2=C(N=C(N1)SCC(NC3=NC=C(S3)S(C4=CC=C(C=C4)[N+]([O-])=O)(=O)=O)=O)C=CC=C2
Molecular Weight: 503.53
References & Citations: [1]Martin Pannek, et al. Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. J Med Chem. 2024 Feb 8;67(3):1843-1860.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-163316-04	SIRT4-IN-1
HY-163316-05	SIRT4-IN-1
HY-163316-03	SIRT4-IN-1
HY-163316-06	SIRT4-IN-1
HY-163316-02	SIRT4-IN-1
HY-163316-01	SIRT4-IN-1
HY-P702908	SIRT4, Human (GST)
HY-RS12946	SIRT4 Human Pre-designed siRNA Set A
HY-151891-04	TASK-1-IN-1
HY-151891-01	TASK-1-IN-1