Mal-Toxophore

• UNSPSC Description:

  Mal-Toxophore is a drug-linker conjugate for ADC and can be used for ADC synthesis. The payload is a NAMPT inhibitor (HY-164759)[1].

• Target Antigen:

  Drug-Linker Conjugates for ADC

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mal-toxophore.html

• Smiles:

  O=C1C=CC(N1CC(NCCCCCN2N=C(C(CC2=O)C)C3=CC=C(NC(N4CC5=C(C4)C=CN=C5)=O)C=C3)=O)=O

• Molecular Weight:

  571.63

• References & Citations:

  [1]Böhnke N, et al. A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy. Bioconjug Chem. 2022 Jun 15;33(6):1210-1221.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2592504-91-9