Anti-BCMA [CA8]

• Gene Name:

  [BCMA]

• NCBI Gene ID:

  1062

• Reactivity:

  Human, Cynomolgus Monkey

• Storage Conditions:

  Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.

• Specificity:

  This antibody binds human and cynomolgus monkey BCMA and does not bind TACI or BAFF-R proteins. BCMA acts as a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. BCMA expression is highest on terminally differentiated B cells. BCMA is involved in mediating the survival of plasma cells for maintaining long-term humoral immunity. It also activates NF-kappa-B and JNK. The expression of BCMA has been linked to a number of cancers, autoimmune disorders, and infectious diseases.

• Other Gene Names:

  [CENPE; CENPE; KIF10; CENP-E; PPP1R61; CENP-E]

• Short Name:

  [BCMA]

• Other Product Names:

  [centromere-associated protein E; Centromere-associated protein E; centromere-associated protein E; kinesin family member 10; kinesin-related protein CENPE; Centromere autoantigen E (312kD); protein phosphatase 1, regulatory subunit 61; centromere protein E, 312kDa; Centromere protein E; CENP-E; Kinesin-related protein CENPE]

• NCBI GI Number:

  71061468

• NCBI Accession Number:

  NP_001804.2

• NCBI GB Accession Number:

  NM_001813.2

• Uniprot Accession Number:

  Q02224