IFN-alpha 7/IFNA7, Human (HEK293, Fc)

IFN-alpha 7/IFNA7, Human (HEK293, Fc)

• UNSPSC Description: IFN-alpha 7 (IFNA7), belongs to type I interferon family, is produced by macrophages with antiviral activities[1]. IFN-alpha 7/IFNA7 Protein, Human (HEK293, Fc) contains 166 a.a. (C24-D189), produced in HEK293 cells with a N-terminal hFc-tag.
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/ifn-alpha-7-protein-human-hek293-fc.html
• Molecular Weight: Approximately 50 kDa.
• References & Citations: [1]Kumagai Y, et al. Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses. Immunity. 2007 Aug;27(2):240-52.|[2]Zhang SY, et al. Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense. Immunol Rev. 2008 Dec;226:29-40.|[3]Raj NB, et al. Identification of a novel virus-responsive sequence in the promoter of murine interferon-alpha genes. J Biol Chem. 1991 Jun 15;266(17):11360-5.|[4]Ding M, et al. Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells. Sci Rep. 2021 Aug 18;11(1):16767.
• Shipping Conditions: Room temperature