Chk1-IN-6
CAT:
804-HY-139901-07
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Chk1-IN-6
- CAS Number: 2428423-77-0
- UNSPSC Description: Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.
- Target Antigen: Checkpoint Kinase (Chk)
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/chk1-in-6.html
- Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: N#CC(C=C1)=NC=C1NC2=NC=C(C(F)(F)F)C(NCCC(C)(C)N)=N2
- Molecular Weight: 365.36
- References & Citations: [1]Jin T, et al. Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile. J Med Chem. 2021 Oct 28;64(20):15069-15090.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported