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Pyk2-IN-2

CAT: 0804-HY-401485-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-401485-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pyk2-IN-2 (compound 13j) is an inhibitor of Pyk2 with an IC50 of FAK kinase of 0.608 μM[1].
CAS Number
1271418-15-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
FAK; Pyk2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pyk2-in-2.html
Purity
98.44
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=NNC(C4=CC5=C(N=CC=C5)C=C4)=C3
Molecular Formula
C27H27N7O
Molecular Weight
465.55
Precautions
H302, H315, H319, H335
References & Citations
[1]Bhattacharya SK, et al. Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors. Bioorg Med Chem Lett. 2012 Dec 15;22 (24) :7523-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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