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Propantheline

CAT: 0804-HY-B1188ASize: 1 EachDry Ice: NoHazardous: No
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Description
Propantheline is an orally active mAChR antagonist. Propantheline can be used in the research of smooth muscle dysfunction, excessive sweating, cramps or spasms of the stomach, intestines or bladder, and involuntary urination[1][2][3].
CAS Number
298-50-0
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/propantheline.html
Solubility
10 mM in DMSO
Smiles
CC([N+](C(C)C)(C)CCOC(C1C2=C(OC3=C1C=CC=C3)C=CC=C2)=O)C
Molecular Formula
C23H30NO3+
Molecular Weight
368.49
References & Citations
[1]J Mokry, et al. Propantheline and in vitro reactivity of urinary bladder smooth muscle in guinea pigs. Bratisl Lek Listy. 2005;106 (4-5) :151-4. |[2]Richard Jewell, et al. Propantheline. xPharm: The Comprehensive Pharmacology Reference. 2007, Pages 1-5. |[3]S Kobayashi, et al. Effects of YM905, a novel muscarinic M3-receptor antagonist, on experimental models of bowel dysfunction in vivo. Jpn J Pharmacol. 2001 Jul;86 (3) :281-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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T61453-01Propantheline
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