Anti-ITGA4+ITGB7 (Abrilumab)-SMCC-DM1 ADC

CAT:

708-ADC-W-2384

Size:

1 mg

Price:

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Description: This ADC product is comprised of an anti-ITGA4+ITGB7 monoclonal antibody conjugated via a SMCC linker to DM1. The DM1 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
CAS Number: 9007-83-4
Format: Solution
Shipping Conditions: Ice Packs
Storage Conditions: -20°C

Cat	Name
ADC-W-2384	Anti-ITGA4+ITGB7 (Abrilumab)-SMCC-DM1 ADC
ADC-W-2492	Anti-ITGA4+ITGB7 (Vedolizumab)-SMCC-DM1 ADC
ADC-W-2498	Anti-ITGA4+ITGB7 (Crenezumab)-SMCC-DM1 ADC
ADC-W-2385	Anti-ITGA4+ITGB7 (Abrilumab)-SPDB-DM4 ADC
ADC-W-2386	Anti-ITGA4+ITGB7 (Abrilumab)-MC-MMAF ADC
ADC-W-1466	Anti-ITGA4 (Natalizumab)-SMCC-DM1 ADC
ADC-W-1472	Anti-ITGA4 (Etrolizumab)-SMCC-DM1 ADC
ADC-W-2388	Anti-ITGA4+ITGB7 (Abrilumab)-MC-Vc-PAB-SN38 ADC
ADC-W-2387	Anti-ITGA4+ITGB7 (Abrilumab)-MC-Vc-PAB-MMAE ADC
ADC-S-009	SMCC-DM1

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