Anti-ERBB2 (Trastuzumab-LC-K149)-DBCO-MMAF ADC

CAT:

708-ADC-W-258

Size:

1 mg

Price:

Ask

For price, please contact [email protected]

Description: This ADC product is comprised of an anti-ERBB2 monoclonal antibody (Trastuzumab variant,LC-K149) conjugated via a DBCO linker to MMAF. The MMAF is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAF binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
CAS Number: 9007-83-4
Format: Solution
Shipping Conditions: Ice Packs
Storage Conditions: -20°C

Cat	Name
ADC-W-258	Anti-ERBB2 (Trastuzumab-LC-K149)-DBCO-MMAF ADC
ADC-W-256	Anti-ERBB2 (Trastuzumab-LC-Q147)-DBCO-MMAF ADC
ADC-W-257	Anti-ERBB2 (Trastuzumab-LC-E161)-DBCO-MMAF ADC
ADC-W-254	Anti-ERBB2 (Trastuzumab-LC-R142)-DBCO-MMAF ADC
ADC-W-255	Anti-ERBB2 (Trastuzumab-LC-N152)-DBCO-MMAF ADC
ADC-W-263	Anti-TNFRSF8 (Brentuximab-LC-K149)-DBCO-MMAF ADC
ADC-W-247	Anti-ERBB2 (Trastuzumab-HC-P127)-DBCO-MMAF ADC
ADC-W-246	Anti-ERBB2 (Trastuzumab-HC-F126)-DBCO-MMAF ADC
ADC-W-242	Anti-ERBB2 (Trastuzumab-HC-K121)-DBCO-MMAF ADC
ADC-W-243	Anti-ERBB2 (Trastuzumab-HC-Y180)-DBCO-MMAF ADC