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A-62198

CAT: 0804-HY-129737Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129737Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A-62198 is a potent and selective renin inhibitor with antihypertensive activity. A-62198 reduces mean arterial pressure (MAP) in anesthetized, salt-deprived monkeys in a dose-dependent manner. A-62198 induced MAP reduction in normal monkeys that reached statistical significance at the highest dose and significantly inhibited plasma renin activity (PRA) at all doses[1].
CAS Number
117978-26-4
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/a-62198.html
Smiles
O[C@@H]([C@H](CN=[N+]=[N-])O)[C@@H](NC([C@H](CC1=CNC=N1)NC([C@H](CC2=CC=CC=C2)NC(C(C)C)=O)=O)=O)CC3CCCCC3
Molecular Formula
C30H44N8O5
Molecular Weight
596.72
References & Citations
[1]Cardiovascular actions of the primate-selective renin inhibitor, A-62198
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
MBS5776161A 62198

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