Products for Research Use Only
RegisterLogin

RO495

CAT: 0804-HY-18316-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-18316-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase) [1].
CAS Number
1258296-60-4
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ro495.html
Purity
98.59
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(NC2=NC(N)=NC(C)=C2)=NC=C1)C3=C(Cl)C=CC=C3Cl
Molecular Formula
C17H14Cl2N6O
Molecular Weight
389.24
References & Citations
[1]Tobie D. Lee, et al. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology November 2019, 96 (5) 629-640.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T22416-01RO495
A22328-50RO495 50mg
A22328-10RO495 10mg
A22328-100RO495 100mg
A22328-25RO495 25mg
A22328-5RO495 5mg
A22328-1RO495 1mg
A22328-200RO495 200mg
A22328-2RO495 2mg
A22328-10mM-DRO495 10mM * 1mL in DMSO

Popular Products