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Sulfatinib

CAT: 0804-HY-12297-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12297-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sulfatinib (Surufatinib) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC50s of in a range of 1 to 24 nM.
CAS Number
1308672-74-3
Product Name Alternative
Surufatinib; HMPL-012
UNSPSC
12352005
Hazard Statement
H315, H317, H318, H334, H335, H341, H361, H370, H413
Target
FGFR; VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/KDR-IN-1.html
Concentration
10mM
Purity
99.52
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=S(CC1=CC=CC(NC2=NC=CC(OC3=CC4=C(NC(C)=C4)C=C3)=N2)=C1)(NCCN(C)C)=O
Molecular Formula
C24H28N6O3S
Molecular Weight
480.58
Precautions
H315, H317, H318, H334, H335, H341, H361, H370, H413
References & Citations
[1]PCT Int. Appl. (2011), WO 2011060746 A1 20110526.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
VEGFR1/Flt-1; VEGFR2/KDR/Flk-1; VEGFR3/Flt-4

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