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Schaftoside

CAT: 0804-HY-N0703-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0703-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission[1].
CAS Number
51938-32-0
UNSPSC
12352005
Target
Autophagy; Dynamin; Mitochondrial Metabolism; MyD88; Toll-like Receptor (TLR)
Type
Natural Products
Related Pathways
Autophagy; Cytoskeleton; Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/schaftoside.html
Purity
99.57
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=C([C@@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO)C(O)=C3C(OC(C4=CC=C(O)C=C4)=CC3=O)=C1[C@H](OC[C@H](O)[C@@H]5O)[C@@H]5O
Molecular Formula
C26H28O14
Molecular Weight
564.49
References & Citations
[1]Zhou K, et al. Schaftoside ameliorates oxygen glucose deprivation-induced inflammation associated with the TLR4/Myd88/Drp1-related mitochondrial fission in BV2 microglia cells. J Pharmacol Sci. 2019 Jan;139 (1) :15-22.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
TLR4

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