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Cloperidone

CAT: 0804-HY-164031Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164031Size:1 Each
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Description
Cloperidone is an inhibitor for cytochrome P450 2C9 (CYP2C9) with an IC50 of 17.7 μM. Cloperidone exhibits cytotoxicity on HepG2 cells expressing CYP2C9 (60% survival rate at 10 μM) [1].
CAS Number
4052-13-5
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cloperidone.html
Smiles
O=C1NC2=C(C(N1CCCN3CCN(CC3)C4=CC(Cl)=CC=C4)=O)C=CC=C2
Molecular Formula
C21H23ClN4O2
Molecular Weight
398.89
References & Citations
[1]Goldwaser E, et al., Machine learning-driven identification of drugs inhibiting cytochrome P450 2C9. PLoS Comput Biol. 2022 Jan 26;18 (1) :e1009820.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Isoform
CYP2C9

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