Adenosine phosphonobutyric, 2'(3'), 5'-diposphate

Adenosine phosphonobutyric, 2'(3'), 5'-diposphate

• CAS Number: 1050202-63-5
• UNSPSC Description: Adenosine phosphonobutyric, 2'(3'), 5'-diposphate (APBADP) is a potent Bacillus subtilis and human adenylosuccinate lyase (ASL) inhibitor. Adenosine phosphonobutyric, 2'(3'), 5'-diposphate also is a competitive succinylaminoimidazole carboxamide ribotide (SAICAR) inhibitor[1].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/adenosine-phosphonobutyric-2-3-5-diposphate.html
• Smiles: O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O[C@H]1N2C(N=CN=C3NC(C(O)=O)CCOP(O)(O)=O)=C3N=C2
• Molecular Weight: 609.27
• References & Citations: [1]Sivendran S, et al. Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens. Protein Sci. 2008 Jul;17(7):1162-74.|[2]Sivendran S, et al. Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens. Protein Sci. 2008 Jul;17(7):1162-74.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported