Products for Research Use Only
RegisterLogin

OX40/TNFRSF4

CAT: 0426-E21-K60Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0426-E21-K60Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs) . The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
Description
Recombinant Human OX40L receptor is produced by our Mammalian expression system and the target gene encoding Leu29-Ala216 is expressed with a 6His tag at the C-terminus.
Synonyms
Tumor necrosis factor receptor superfamily member 4; TNFRSF4; OX40; CD134; Txgp1
Expression System
Human Cells
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Shipping Conditions
The product is shipped at ambient temperature.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Species
Human
Shipping Temperature
Ambient

Related Products

CatalogName
E55A05927Human CD134/TNFRSF4/OX40 Antibody
E55A06381Mouse CD134/TNFRSF4/OX40 Antibody
E55A06800Human CD134/TNFRSF4/OX40 Antibody
E55A05928Human CD134/TNFRSF4/OX40 Antibody
E55A14366Human CD134/TNFRSF4/OX40 Antibody
E55A10540Human CD134/TNFRSF4/OX40 Antibody , PE
E55A10542Mouse CD134/TNFRSF4/OX40 Antibody , PE
E55A07518Human CD134/TNFRSF4/OX40 Antibody , FITC
E55A07519Human CD134/TNFRSF4/OX40 Antibody , FITC
E55A07520Human CD134/TNFRSF4/OX40 Antibody , FITC

Alternative Products

CatalogName
MBS8533009-01OX40/TNFRSF4
MO47051OX40/CD134/TNFRSF4
GTR18713379-01OX40 (TNFRSF4) Antibody
GTR18574584OX40 Antibody / CD134 / TNFRSF4
GTR18311721-01TNFRSF4/OX40/CD134 Antibody
Z03438-100OX40/TNFRSF4, His, Human
GTR18226180TNFRSF4/CD134/OX40 Antibody
IT-300-039p-01Human TNFRSF4 / OX40 / CD134
PROTP47741-1-20ugMouse recombinant OX40/TNFRSF4 protein
PROTP43489-2-500ugHuman recombinant OX40/TNFRSF4 protein

Popular Products