Products for Research Use Only
RegisterLogin

Sonic Hedgehog/Shh

CAT: 0426-E21-H69Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0426-E21-H69Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH) . Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N­terminal fragment (Shh­N), and a catalytic­processing, glycosylated, 34 kDa, 239 aa C­terminal fragment. The 20 kDa Shh­N fragment is the core of the active hedgehog molecule. Mouse Shh­N is 99%, 98%, and 100% aa identical to human, rat and gerbil Shh­N, respectively.
Description
Recombinant Mouse Sonic Hedgehog is produced by our E.coli expression system and the target gene encoding Cys25-Gly198 is expressed.
Synonyms
Sonic Hedgehog Protein; SHH; HHG-1; SHH
Expression System
E. Coli
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Shipping Conditions
The product is shipped at ambient temperature.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.
Species
Mouse
Shipping Temperature
Ambient

Related Products

CatalogName
E2220715SHH/Sonic Hedgehog Mouse mAb
E40KMP1648Recombinant Mouse Shh/Sonic Hedgehog Protein
E8ET1610-6Sonic Hedgehog Protein/SHH (C-Product)
E28PE0120SHH (Sonic Hedgehog) (12H9) Mouse Monoclonal antibody
E901561PRecombinant Mouse Sonic hedgehog protein N-product/SHH Protein
E900056PRecombinant Human Sonic hedgehog protein N-product/SHH (C24IVI) Protein
E2380722Sonic Hedgehog Rabbit pAb
E2347501Sonic Hedgehog Rabbit pAb
E60M1148Sonic Hedgehog Rabbit mAb
E2R380722Sonic Hedgehog Rabbit mAb

Alternative Products

CatalogName
MBS6508259-01Shh (Sonic HedgeHog)
NBP2-35339-5ugSonic Hedgehog/Shh
491674SHH (Sonic Hedgehog Protein, Sonic Hedgehog)
216959Sonic Hedgehog (SHH)
S1012-96GSHH (Sonic HedgeHog, Sonic Hedgehog Protein, SHH, HHG-1)
F53264-0.4MLShh Antibody / Sonic Hedgehog
RC444717Mouse Sonic HedgeHog (shh)
140627Hedgehog Homolog, Sonic (SHH)
Z05851-500Sonic Hedgehog (Shh), Human
HC77758Human Sonic HedgeHog (Shh)

Popular Products