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Cadherin-3/CDH3

CAT: 0426-E21-968Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0426-E21-968Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
Description
Recombinant Human Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu25-Gly654 is expressed with a 6His tag at the C-terminus.
Synonyms
Cadherin-3; Placental Cadherin; P-Cadherin; CDH3; CDHP
Expression System
Human Cells
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Shipping Conditions
The product is shipped at ambient temperature.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Species
Human
Shipping Temperature
Ambient

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Alternative Products

CatalogName
308730-01Cadherin-3 (CDH3)
MBS8532919-01Cadherin-3/CDH3
MBS6013120-01CDH3, NT (CDH3, CDHP, Cadherin-3, Placental cadherin)
MBS6004891-01CDH3, CT (CDH3, CDHP, Cadherin-3, Placental cadherin)
MBS6284192-01CDH3, NT (CDH3, CDHP, Cadherin-3, Placental cadherin) (PE)
MBS6284183-01CDH3, NT (CDH3, CDHP, Cadherin-3, Placental cadherin) (APC)
MBS6284182-01CDH3, NT (CDH3, CDHP, Cadherin-3, Placental cadherin) (AP)
MBS6284174-01CDH3, CT (CDH3, CDHP, Cadherin-3, Placental cadherin) (FITC)
MBS6284173-01CDH3, CT (CDH3, CDHP, Cadherin-3, Placental cadherin) (Biotin)
MBS6284172-01CDH3, CT (CDH3, CDHP, Cadherin-3, Placental cadherin) (APC)

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